RCT2015
Sinus ComfortSupports healthy sinuses
Mucus BalancePromotes natural mucus flow
Clear AirwaysBreathe comfortably
Nasal ComfortComfortable nasal airflow
HistPro
Targeted botanical capsules with quercetin and butterbur, whose petasins support a normal histamine and leukotriene response and healthy respiratory function.
- Histamine Balance
- Seasonal Comfort
- Immune Support
- Breathe Easy
- Butterbur to maintain comfortable nasal airflow
- Promotes a balanced histamine response
- Helps healthy mucus clearance
- Supports healthy respiratory function
- Vitamin C supports the body's antioxidant defenses
Regular price
$47.00
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Benefits
- Supports clear, comfortable breathing
- Promotes a balanced histamine response
- Helps healthy mucus clearance
- Bromelain supports normal immune cell signaling and healthy immune function
- Quercetin to support a normal, healthy inflammatory response
Who It's For
How To Use
- Take 2 capsules daily, or as directed by your qualified healthcare practitioner.
Quality You Can Trust
- We consider purity and quality non-negotiable. Every batch is tested in an ISO/IEC 17025-accredited laboratory before it reaches you. The laboratory testing screens for heavy metals, microbials, other known contaminants, and ensures that the actual dosages match what's stated on the label (potency). It's how we can stand behind the purity, safety and consistency of every bottle.
Noticeable Improvements!
“I suffered from histamine reactions, asthma & allergies. I was using an inhaler daily & when I started HistPro for the 1st year, I was down to using my inhaler every quarter & then went through a period where I stopped taking it & immediately felt histamines come back, itchy eyes etc. I went back on it over the last few months & immediately felt better.”
Sue H
Verified Customer
HistPro
The EquiLife Advantage
Science-Backed Ingredients
What's Inside One Serving
- Vitamin CSupports a healthy immune system
- QuercetinA flavonoid included to support a balanced histamine response
- Stinging Nettle Root400mg of nettle root per 2-capsule serving
- BromelainA plant enzyme included to support healthy sinus function and comfort
- ButterburPetasins support a normal histamine and leukotriene response
Supplement Facts
Serving Size
2 Capsules
Servings Per Container
30
Amount Per Serving% Daily Value
- Vitamin C (as Ascorbic Acid) 300 mg333%
- Quercetin 400 mg*
- Stinging Nettle Root 400 mg*
- Perilla Fruit Extract 150 mg*
- Bromelain 100 mg*
- Purple Butterbur Root Extract 75 mg*
- Petasins 11.25 mg*
- N-Acetyl Cysteine 50 mg*
*Daily Value (DV) not established.
Other ingredients: Hydroxypropyl methylcellulose and rice hull extract.
Supplement Facts
Serving Size
2 Capsules
Servings Per Container
30
Amount Per Serving% Daily Value
- Vitamin C (as Ascorbic Acid) 300 mg333%
- Quercetin 400 mg
- Stinging Nettle Root 400 mg
- Perilla Fruit Extract 150 mg
- Bromelain 100 mg
- Purple Butterbur Root Extract 75 mg
- Petasins 11.25 mg
- N-Acetyl Cysteine 50 mg
Other ingredients: Hydroxypropyl methylcellulose and rice hull extract.
SEASONAL SUPPORT, DAILY
Histamine Balance and Clear, Comfortable Breathing
HistPro combines flavonoids, antioxidants, enzymes, and botanicals to support a balanced histamine response, comfortable nasal airflow, and healthy respiratory function.
- SINUS COMFORT
- CLEAR AIRWAYS
- IMMUNITY
- BOTANICALS & HERBS
- NO SOY
- NO DAIRY
- NO GLUTEN
- NO EGGS
- Sinus ComfortSupports Healthy Sinuses
- Mucus BalancePromotes Natural Mucus Flow
- Clear AirwaysBreathe Easy
- Seasonal SupportComfortable Nasal Airflow
- Histamine BalanceBalanced Histamine Response
By The Numbers
High Standards Meet Proven Results
1,200
Scientific Citations
supporting the ingredients and formulations used across EquiLife nutritional supplements.
300,000+
Lab Tests
& 1-on-1 appointments helping people uncover personalized insights into their health.
1M+
Customer Orders
Fulfilled globally across EquiLife labs, protocols, and nutritional supplements.
26 Years
Clinical Experience
behind the health mission, data, protocols & products that shape EquiLife & our customer results.
Quality You Can Trust
Every Batch is Tested For Purity, Potency & Proper Composition
Purity and quality are non-negotiable. Every batch of EquiLife supplements is tested by an ISO/IEC 17025-accredited laboratory before it reaches you. Testing screens for heavy metals, microbes, and other known contaminants, while also ensuring that the ingredients and dosages match what's listed on the label. This rigorous testing helps ensure every bottle meets our standards for purity, potency, and consistency.
Board Certified Doctor of Naturopathy
Created By Dr. Stephen Cabral
Getting Better Together.
“EquiLife goes beyond lab testing, protocols, and formulas. It's my life's work, built on combining ancient wisdom with modern science. Every formula is one I would use, and do use, with my own family.”
Dr. Stephen Cabral EquiLife Founder
EquiLife Founder
26 Years in Private Practice
300,000+ 1:1 Client Appointments
6+ Million Biomarkers Tested
The 60-Day Empty Bottle Guarantee
If you don't love your EquiLife product, send it back for a full refund — even if the bottle is empty.
Substantiated by published research
The Science Behind HistPro
Every dose-matched benefit listed for HistPro is tied to a specific ingredient in this formula, at a dose equal to or greater than the amount studied, and to the peer-reviewed research that supports it. Ordered by relevance to what this product is designed to do.
HistPro lists 14 research-backed benefits across 3 ingredients, supported by 14 peer-reviewed studies (3 human trials).
- Benefits
- 14
- Studies cited
- 14
- Human trials
- 3
- Dose matched
- 14/14
Sort by
Highest-tier evidence per benefit
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RCT2009
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Study2010
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RCT2009
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Study2010
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RCT2009
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Study2010
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Study2015
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Study2019
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Study2004
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Study2005
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No published research summary is available for this option yet.
If You Have Questions, We Have Answers.
Frequently Asked Questions
Who formulates EquiLife products?
Every EquiLife supplement is formulated by Dr. Stephen Cabral, a Board Certified Doctor of Naturopathy with more than two decades of clinical experience helping clients through his private practice. Formulation starts from a simple standard: Dr. Cabral only creates products he'd give to his own family and his own practice clients. That means choosing the most bioavailable, body-ready forms of each nutrient (for example, methylated B vitamins), pairing ingredients that work well together, and refusing to cut corners on quality even when a better raw material costs more. It's a practitioner-first philosophy rather than a mass-market one.
Are EquiLife supplements gluten-free, non-GMO, and free from common allergens?
We formulate with a clean-label standard, so most EquiLife supplements are gluten-free, all are non-GMO, and free from dairy, soy, egg, and nut ingredients, with no artificial colors, preservatives, or unnecessary fillers. Most of our products are also vegan. Because attributes vary by product, we list the specific dietary details right on each product page and label, so you can confirm the exact profile of anything before you buy.
Are EquiLife products science-informed and grounded in research?
Our formulas are grounded in published nutritional research, clinical experience, and functional-medicine principles. For each product, ingredients and dosages are selected based on the available scientific literature and Dr. Cabral's real-world clinical use - not on trends or marketing fads. Our goal is to give your body well-researched nutrients in forms it can actually absorb and use.
Does EquiLife test its supplements for purity and quality?
Yes, and we consider it non-negotiable. Every batch is tested by an independent lab before it reaches you. The laboratory testing screens include heavy metals, mold, and bacteria, checks for impurities, and confirms that the actual dosages match what's stated on the label (potency). It's how we can stand behind the purity, safety, and consistency of every bottle.
Where are EquiLife supplements manufactured?
Our nutritional supplements are manufactured and stored in the United States at GMP facilities, under strict quality controls. We also keep production fresh, made in smaller, continuous batch runs every couple of months rather than products sitting in a warehouse.
How do I know which EquiLife supplements are right for me?
You don't have to guess. Unlike a commodity supplement brand, EquiLife helps you personalize your path. You can start with our online quizzes and wellness protocols, work with our health coaches, or go deeper with at-home functional lab testing to understand your body's specific needs. From there, we help you build a routine designed around you—not a one-size-fits-all shelf product.
How long should I take an EquiLife supplement before expecting results?
It depends on each case. Timing varies from person to person and product to product, and is influenced by your diet, lifestyle, baseline nutrient status, and how consistently you take the product. Some people notice changes relatively quickly, while foundational nutrition and longer-term goals often take more time and steady daily use. Consistency is the most important factor we’ve seen over the past 26+ years.
Where does EquiLife ship?
We ship across the United States and to 20+ International countries. Domestic orders over $99 ship free; orders under $99 are a $7.95 flat rate. Please allow about 3–5 business days for processing and shipping, with a little extra time for Alaska, Hawaii, and Puerto Rico. We ship supplements and protocols to more than 20 countries internationally (Australia, Austria, Canada, Denmark, France, Greece, Hong Kong, Hungary, Iceland, Italy, Latvia, Netherlands, New Zealand, Norway, Philippines, Romania, Singapore, Sweden, Switzerland, Taiwan, Ukraine, United Kingdom, Vietnam) and at-home lab tests to a smaller set (Australia, Canada, New Zealand, and the United Kingdom). International duties, taxes, and VAT are calculated at checkout. For the full country list and details, see our Shipping page.
How does an EquiLife subscription work, and can I change or cancel it?
Subscribing is the easiest way to stay consistent; which is the single biggest factor in getting results. When you choose the subscribe option on any eligible product, your order ships automatically on the schedule you select, and you'll save 15–20% on every recurring order versus one-time pricing. You're always in control: you can skip a shipment, change your delivery frequency, swap products, update your address or payment, or cancel anytime from your online account—no phone calls or emails required. And because your supplements arrive automatically, you never have to worry about running out mid-routine.
Does EquiLife offer a satisfaction guarantee?
Yes. We stand behind every product with our "Empty Bottle 100% Satisfaction Guarantee." If you're not satisfied, simply return your empty bottles within 60 days of purchase for a full refund of your product purchase price (shipping and handling excluded). At-home lab tests are also refundable if returned before lab processing begins.
Our Customers Are Our Best Advocates
V
We’re now on our second bottle.Neither of us have had any issues. It works!
J
Feeling better because of your products. Thank you
N
My husband has been taking it and says he's really noticed a difference after starting
A
I’ve had some problems with histamine. I’ve been taking this for several months and notice a difference when I take it. I’ve had no issues tolerating it.
A
My husband was struggling with a lot of histamine related symptoms and this was the one product that really made a difference after trying many other things. He finds it most helpful to use 2 capsules 2 or 3 times a day. We love this product.
H
I’ve been working through some histamine issues for a while and this does seem to be helping.
E
Like all Equilife products I have used, it helped me with nighttime itching and nasal congestion. It’s even slightly stimulating for me and I take it in the am now versus the evening. You have to adjust it to your own biochemistry. Great product.
G
When I first tried this a year ago, it seemed to work quite well. I just bought 3 more bottles. I am having the same issues as before and now it doesn't seem to work at all after taking for 4 days. If the situation changes, I will come back and update this review. Otherwise, this is a bust for me for now,
H
I bought this while it was on sale to stock up. The bottle was half the size of what I normally get, so the cost was the same. I love the product just unsure what the quantity is less but price stayed the same.
M
HistPro
C
Works great!!
A
HistPro
J
I was skeptical at first but I’ve been pleasantly surprised I haven’t had any allergy flare ups this year. Great product!
L
Great product. I instantly noticed it was easier to breath through my nose
L
I love all the products I buy from equi.life!
C
HistPro
K
Good product along with the other immunity products
J
I only used it one day and stopped. Gave me stomach problems
B
I found it helpful for my seasonal sensitivities
J
Seems to be helping my GI settle down and be less inflamed. Thank you!
K
This product is amazing, I take it everyday.
L
Love the ingredients in this one supplement. Great product!
B
HistPro
M
I love the combination of supplements in Histpro - it’s the best I’ve found out there! One I will always keep on hand at home.
I
no need for any medications that make me drowsy when I have hayfever!
C
This product isn't just healing, but it tastes so great! I sometimes put it in my shake and other times mix it in with my coffee and some oat milk and it is delish! I love that these products are not just good for the body and health, but they taste so good as well.
W
"Did you take your Histpro?" That is what I ask my husband if he starts to snore at night. 99.9% of the time if he has not taken it, that is why he is snoring. I am not sure I can claim this is a stop snoring aid but it sure works in my house!
T
HistPro
N
It’s good
L
I have always struggled with seasonal allergies and this year it developed into more of a mucus build up that was super annoying. I started the HistPro and it helped decrease the post nasal drip I was having. I never let this bottle run low, because if I don’t take it daily, I can definitely tell!
I
my son suffers from dust mite allergies and instead of taking anti histamines this has helped clear up his sinus issues.
M
This supplement has helped immensely with my histamine/mast cell issues. I've tried quercetin, stinging nettle and vitamin c on their own with little improvement but this product combines them all and adds other great herbs and vitamins to give you relief from annoying allergy symptoms. I highly recommend it :)
